(updated Mar/2012) If you've used the excellent Regex Coach for Perl programmers on Windows but have been dissapointed that the current version does not run on Mac OS/X, fear not. You can build Wine and then it runs well.
  1. Install HomeBrew
  2. Run the command brew install wine && brew install winetricks && winetricks vcrun2005
  3. Download the Regex Coach installer
  4. Run the command wine regex-coach.exe to install
  5. To run Regex Coach run the command wine ~/.wine/drive_c/Program\ Files/The\ Regex\ Coach/The\ Regex\ Coach.exe

The equivalent process also works for the Linux